Martin R. Schiller
Associate Professor
Ph.D. Utah State University, Utah
Bioinformatics
Martin R. Schiler is an Associate Professor in the School of Life Sciences at the University of 
Nevada, Las Vegas. His research focuses on building bioinformatics tools to forward biological discovery. These tools include Minimotif Miner, HIVTolbox, VENN, MimoSA, and JBOG which can be accessed at the Bio-toolkit website. Each tool is connected with a set of experiments that test hypotheses.
Publications (since 2005)
Gradie PR, Litster M, Thomas R, Vyas J, Schiller MR. (2011) SciReader enables reading of medical content with instantaneous definitions BMC Med. Inf. and Decision Making 11, 4 PMID: PMID: 21266060
Kaneko T, Huang H, Zhao B, Li L, Liu H, Voss CK, Wu C, Schiller MR, Li SS.. (2010). Loops govern SH2 domain specificity by controlling access to binding pockets. Science Signaling, 3, RA34. PMID: 20442417
Jay Vyas, Ronald J.Nowling, Thomas Meusberger, David Sargeant, Krishna Kadaveru. Michael R. Gryk, Vamsi Kundeti Sanguthevar Rajasekaran and Martin R. Schiller. (2010). MimoSA: a system for minimotif annotation. BMC Bioinformatics, 11, 328. PMID: 19656955
Rajasekaran S, Mi T, Camilus J, Vyas J, Schiller MR. (2010). Partitioning of Minimotifs Based on Function with Improved Prediction Accuracy. Plos One, 19, pii: e12276. 20808856
Rajasekaran S, Merlin JC, Kundeti V, Mi T, Oommen A, Vyas J, Alaniz I, Chung K, Chowdhury F, Deverasatty S, Irvey TM, Lacambacal D, Lara D, Panchangam S, Rathnayake V, Watts P, Schiller MR. (2011). A computational tool for identifying minimotifs in protein-protein interactions and improving the accuracy of minimotif predictions.Proteins, 79: 153-164, PMID: 20938975
Vyas J, Gryk MR, and Schiller. (2009). Venn, a tool for titrating sequence conservation onto protein structures. Nucleic Acids Res., 37, e124. PMID: 19656955
Vyas J, Nowling RJ, Maciejewski MW, Rajasekaran S, Gryk MR, and Schiller MR. (2009). A Proposed Syntax for Minimotif Semantics, Version 1. BMC Genomics., 10, 360. PMID: 19656396
Rajasekaran S, Balla S, Gradie P, Gryk MR, Kadaveru K, Kundeti V, Maciejewski MW, Mi T, Rubino N, Vyas J, Schiller MR. (2009). Minimotif Miner 2nd release: a database and web system for motif search. Nucleic. Acids Res.,37, D185-190. PMID: 18978024
Fox-Erlich S, Schiller MR, Gryk MR. (2009). Structural Conservation of a short, functional, peptide sequence motif.Front. Biosci., 14, 1143-1151. PMID: 19273121
Schiller MR*, Ferraro F, Wang Y, McPherson CE, Sobota J, Schiller NI and Eipper BA. (2008). Autonomous functions for the Sec14p and spectrin-repeat regions of Kalirin. Exp. Cell Res., 314, 2674-2691. PMID: 18585704
Krishna Kadaveru K, Vyas J, and Schiller MR. (2008). Viral infection and human disease - insights from minimotifs.Front. Biosci., 6455-6471. PMID: 18508672
Machida K, Thompson CM, Dierck K, Jablonowski , K Karkkainen S, Liu B, Zhang H, Nash PD, Newman DK, Nollau P, Pawson T, Renkema, GH, Saksela K, Schiller MR, Shin DG, and Mayer BJ. (2007). High-Throughput Phosphotyrosine Profiling Using SH2 Domains. Mol. Cell, 26, 899-915. PMID: 17588523
Schiller MR*. (2007). Minimotif Miner, a computational tool to investigate protein function, disease, and genetic diversity. Current Protocols in Protein Science, Eds. Coligan JE, Dunn BM, Speicher DW, Winkler H., Unit 2.12.1 - 2.12.14. PMID: 18429315
Zhang G, Hirai H, Cai T, Miura J, Yu P, Huang H, Schiller MR, Swaim WD, Leapman RD, and Notkins AL. (2007). RESP18, a homolog of the luminal domain IA-2, is found in dense core vesicles in pancreatic islet cells and is induced by high glucose. J. Endocrinol., 195, 313-321. PMID: 17951542
Balla S, Thapar V, Verma S, Luong T, Faghri T, Huang C-H, Rajasekaran S, del Campo JJ, Shinn JH, Mohler WA, Maciejewski MW, Gryk MR, Piccirillo B, Schiller SR, and Schiller MR. (2006). Minimotif Miner, a tool for investigating protein function.. Nat. Methods, 3, 175-177. PMID: 16489333
Schiller MR*. (2006). Coupling Receptor Tyrosine Kinases to Rho GTPases - GEFs what's the link. Cell. Signal., 18, 1834-1843. PMID: 16725310
Schiller MR*, Chakrabarti K, King GF, Schiller NI, Eipper BA, and Maciejewski MW. (2006). Regulation of RhoGEF activity by intramolecular and intermolecular SH3 interactions. J. Biol. Chem., 281, 17774-17786. PMID: 16644733
Rajasekaran S, Balla S, Huang C, Thapar C, Gryk M, Maciejewski M, and Schiller M.. (2005). High Performance Algorithms for Motif Search. J. Clin. Mon. Comp., 19, 319-328. PMID: 16328946
Chakrabarti K, Lin R, Schiller NI, Wang Y, Fan Y-X, Koubi D, Rudkin BB, Johnson GR, Schiller MR. (2005). A critical role for Kalirin in NGF signaling through TrkA. Mol. Cell. Biol., 25, 5106-5118. PMID: 15923627
Faculty
Contact
- Office: WHI 117
- Lab: WHI 118, 119
- Phone
- Office: 702.895.5546
- Lab: 702.895.1271
- Fax: 702.895.5728